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  • Anti-psychotic medications are very useful and have helped many people with schizophrenia

  • to lead healthy and productive lives by taking care of some of the symptoms, including delusions,

  • hallucinations, disorganized thinking, disorganized behavior, and negative symptoms, or lack of

  • motivation that may come with schizophrenia. However, they don't come without side effects.

  • I'm going to talk with you about four different categories of side effects that seem to be

  • very common.

  • One is what we call extrapyramidal symptoms. Those are motor or movement side effects of

  • these medications. The older anti-psychotics tend to have more of these side effects. They

  • include feeling stiff in your muscles, having tremor in your hands or in your body, feeling

  • restless and unable to sit still, or having what we call tardive dyskynesia. That occurs

  • over time, where you might have movements of your mouth or of your limbs that are repetitive

  • and that appear after a period of treatment. Those are the extrapyramidal symptoms, or

  • EPS. They're more common with the older medications.

  • With the newer medications, the more common side effects tend to be what we call the metabolic

  • side effects, or cardiometabolic side effects. Those include weight gain, an increased blood

  • sugar or risk for diabetes, and an increased cholesterol. Initially, we were really excited

  • about all of the new anti-psychotic medications.

  • Then, when we saw how people gained weight and got more heart disease, partly related

  • to the medications, we started to see that there was a big risk there, because really,

  • it's heart disease and diabetes that tend to be the things that lead to early mortality

  • in people with schizophrenia. So, that's the second category of side effects.

  • There's also anticholinergic side effects. Those include dry mouth, feeling flushed or

  • hot, having constipation. Those are things that tend to happen with the anticholinergic

  • side effects. Different medications, both old and new, have more or less anticholinergic

  • side effects.

  • One last category that I'll mention is prolactin. Prolactin is a body hormone that you have.

  • For some of our anti-psychotic medications, in particular Risperidone, is probably the

  • biggest culprit, increase prolactin production. What happens, then, is that women especially

  • may not have their periods, they may have difficulty conceiving a child. And, for some

  • people, there's breast enlargement and even lactation, both men and women. That can be

  • a very disruptive side effect, obviously, and needs to be addressed.

  • If you have side effects with anti-psychotic medications, definitely, there's many choices

  • of anti-psychotic medication, and so you should speak with your doctor or psychiatrist about

  • it, because they can try different things to see what works best for you and causes

  • the least burden of side effects to you. Many people have no side effects at all from anti-psychotic

  • medications, thank goodness. If you have schizophrenia and you're thinking about medications, find

  • a treatment provider you trust so you can work on finding the right medication for you.

Anti-psychotic medications are very useful and have helped many people with schizophrenia

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抗精神病薬の副作用|統合失調症 (Side Effects of Antipsychotic Drugs | Schizophrenia)

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    amychan248 に公開 2021 年 01 月 14 日
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