Name: Fasting to Detox（Fasting to Detox）
Uploaded: 2023-07-17T05:23:20.000Z
Duration: 6 min 1 s
Description: VoiceTubeの動画で発音を聞きながら英語表現を覚えよう！学べる英語：

Most persistent industrial pollutants, like organochlorine pesticides

such as DDT and PCBs, were banned several decades ago,

and dioxin emission is strictly regulated.

However, we're still exposed to these chemicals through several routes,

the major source of which is contaminated food,

especially fatty animal products such as fish, meat, and milk.

When we eat these chemicals, they get primarily stored

in our own fatty tissue where they slowly leach out

into our bloodstream, but better in our fat

Having more body fat may actually play a protective role

but they can come spilling out when we lose weight.

Body weight loss increases the concentrations

of potentially toxic pollutants in obese individuals.

Of the 19 pollutants studied, they all went up,

Every study that has looked at it found increased blood levels

of toxic pollutants accompanying weight loss

whether induced by diet or bariatric surgery:

increases between 14 and 388 percent with a large enough loss.

The more weight that's lost, the higher the pollutant levels

climb because all those chemicals stored in your fat

The theoretical concern is that if released into the blood

the levels of these compounds could become toxic,

causing side effects, such as sweating, headache, and nausea,

but the opposite happened when PCB-poisoned patients were fasted.

In 1979, about 2000 people in Taiwan were exposed

via an industrial accident that contaminated rice oil,

leading them to have a higher body toxicity burden

than even long-time consumers of seafood.

all 16 patients they tried it on showed improvements,

with some enjoying dramatic relief of their sufferings,

but this was after just a few days of fasting;

so, they couldn't have really lost that much body fat.

And, they didn't measure PCBs before and after;

so, it's not clear they were experiencing some sort of detox,

The initial rise in pollutant levels in the first year

of weight loss may eventually stabilize or fall.

a remarkable experiment designed to be a completely closed ecosystem,

the longest sustained period of humans isolated

into a 2-year experiment of calorie restriction.

They all lost about 25 pounds in the first 6 months

and stabilized there, and while the levels of PCBs

and a DDT metabolite known as DDE initially went up,

That's one of the reasons health authorities recommend women

don't try to slim down during breast-feeding.

For example, here's a woman whose breast milk levels

jumped up after she had fasted and lost about 20 pounds.

Because fat is mobilized into breast milk,

the secretion of human milk is a major way

these pollutants are eliminated from the mother's body.

Breast is still best regardless, but you can keep your levels lower

by not going out of your way to lose weight

What can one do to help flush the contaminants during weight loss?

One of the reasons the pollutant levels in the biosphere subjects

eventually dropped is because they were eating a high fiber diet

centered around fruits, whole grains, beans, nuts, and vegetables,

and we know that fiber can bind to these pollutants

and potentially flush them out of the body.

So, when losing weight, eating lots of whole grains

may be important to increase the elimination of pollutants

while, of course, cutting down on animal fat, including fish,

so you don't pile on extra at the same time.

What was the dietary intervention in this randomized trial

to decrease the body burden of pollutants?

Subjects were randomized to 24 fat-free Pringles

It all started with this crazy case report of a guy

heavily contaminated by PCBs who managed to rid himself

of 90 percent by losing weight eating potato chips

made out of the fake fat olestra, which doesn't get absorbed,

and so appears to pull pollutants out of the bloodstream

It works in mice, increasing the excretion of hexachlorobenzene

30-fold and cutting the levels in their brains in half,

but in people, the drop in PCB blood levels with the olestra Pringles

was not statistically significantly greater, and for some reason,

LDL bad cholesterol levels shot up 28 points in the olestra group.

And, while olestra and drugs like cholestyramine may absorb

pollutants and remove them from your system,

they also may cause you to dump fat-soluble vitamins.

losing pollution without losing vitamins,

Instead of olestra supplementation to detox,

why not try to not tox so much in the first place.

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Fasting to Detox（Fasting to Detox）

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