Name: オバマ大統領が2014年ホワイトハウス科学フェアを視察 (President Obama Tours the 2014 White House Science Fair)
Uploaded: 2021-01-14T05:11:38.000Z
Duration: 28 min 32 s
Description: VoiceTubeの動画で発音を聞きながら英語表現を覚えよう！学べる英語：

The President: Hello Science Fair participants.

The President: It's kind of intimidating.

The President: Well we're so proud of you.

Alana Simon: Thank you very much, Mr. President.

So, the, I don't know if folks are aware of this story,

They're all remarkable, but I think it's appropriate

And Alana, here is a picture of you when you got sick.

Alana Simon: Well, when I was 12 years old,

I was diagnosed with a rare form of pediatric liver cancer,

called fibrolamellar hepatocellular carcinoma.

The President: That's so impressive that you can say it.

Alana Simon: And not many people know much about the disease.

But I was lucky in that they caught it early enough.

So through, you know, a liver surgery in which they resected

most of my liver, they were able to get the entire tumor out.

And I've been completely ever since, which is incredible.

Alana Simon: So then, a couple of years later,

I had this internship at Cancer Research Lab,

and I learned about this thing called genetic sequencing --

Alana Simon: Where you look through someone's DNA,

which is the stuff that codes for, you know,

And you'll get people's normal cells and their tumor cells,

and you try to figure out what the difference is,

Alana Simon: And I realized that would be perfect

for fibrolamellar, because you don't have to have

some kind of base understanding of the disease.

And as a pediatric cancer, it seemed to be perfect for,

you know, looking at your DNA to find the (inaudible) mutations

Alana Simon: Because, since you're younger,

Alana Simon: So, I talked to my surgeon actually, who had,

And he mentored me, and he actually got a lot of the

samples that I used, and he helped me start this process,

where I was doing genetic sequencing on the kind

And what we ended up finding is this one common mutation

in every single case that we've looked at,

Alana Simon: So, if you'll get to use some nice

Alana Simon: So, chromosomes are where you have all

of your DNA stored, which has your genes that it codes

And so here, in blue, I have one gene, and in green,

And what happens in fibrolamellar patients,

Alana Simon: And here is a person with cancer.

And so, yeah, you can see, there's this one deletion.

So if you look at this, this middle part gets deleted --

Alana Simon: Its noodles, these two genes fused together.

And you get this weird chimera gene, like chimera is, you know,

from Greek mythology, you have the head of one create and the

Alana Simon: You have the head of one gene,

And so, that's what happened in these fibrolamellar patients.

And when these two genes are fused together,

this weird new chimera protein is what then goes into and turns

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オバマ大統領が2014年ホワイトハウス科学フェアを視察 (President Obama Tours the 2014 White House Science Fair)

kind

good

president

yeah