字幕表 動画を再生する 英語字幕をプリント Candida auris is the new superbug on the block you've probably never heard of. This stealthy, drug-resistant yeast can already be found in hospitals worldwide, preying on those with weakened immune systems. The fungus is so prolific that the CDC recently added it to its list of urgent threats. So what exactly is candida auris and how did it fly under the radar to emerge as a global health threat? The feature of Candida auris is not so much the infection that it caused, but the fact that it can spread. And where did it come from? You know, where was it before 2009? That's the million dollar question. Dr Zelazny is right. Candida auris kind of came out of nowhere. Unlike other fungi, this yeast can only be found in people, which has scientists completely stumped. The very first case of C. auris was confirmed when the fungus was isolated from the ear canal of a 70-year-old Japanese woman as recently as 2009 and since then, it's spread rapidly across the globe. Now, you may have heard of Candida, it's a term used for a genus of yeasts that are responsible for the most common fungal infections worldwide. Most healthy adults, like you and me, have a type of candida, called candida albicans, living all over our skin, as well as within our throat and gut. This yeast usually doesn't do any harm, but given the right conditions, it can flourish, and cause opportunistic infections; think athlete's foot, jock itch and thrush. And those types of infections are usually treatable, but that's not the case with C. auris. Most candida auris are resistant to fluconazole, which is a very common antifungal used to treat the candida albicans. Another reason why C. auris poses such a threat is because its symptoms mimic other common candida infections, making it incredibly difficult to diagnose in the first place. Candida auris doesn't have any specific symptoms different from any other Candidas. So it will be fever, if the patient has a sepsis or a blood infection. If the patient has an urinary infection could be itching, going to the bathroom or can be pain. And since it can be easily confused with other yeast infections, special laboratory tests are needed to specifically diagnose C. auris. Only certain labs, like the NIH, that use more advanced technologies like MALDI-TOF mass spectrometry or sequencing, could reliably identify Candida auris. And identifying C. auris quickly is crucial since once the fungus enters the bloodstream, it can be fatal, with a mortality rate between 30 and 60 percent. And that high mortality rate is partly because C. auris preys on the sick. For reasons completely understood by researchers, the fungus is able to spread rapidly in hospitals and nursing homes. It clings to everything from medical equipment to beds, clothing, walls, ceilings, and even window shades, remaining on surfaces for several weeks on end. If you combine spreading from patient to patient, surviving in the hospital environment, even after the patient left, and antifungal resistance, then you have a cocktail that could qualify you as superbug. Oh and if that's not scary enough, C. auris is also resistant to disinfectants. Hospitals are now using specialized cleaning equipment and some have even been forced to take more extreme measures like replacing floorboards and ceiling tiles to completely get rid of the deadly fungus. And to try and stem the ongoing spread of C. auris, scientists are scrambling to try and solve the mystery of its transmission. Yeah, that's another question that people don't know yet. Skin seems to be the site where it leaps. So perhaps transmissions through instrumentation. And since its emergence on the world stage, there have been four types, or clades, of Candida auris identified worldwide: from East Asia, South Asia, South Africa, and South America. So far, roughly 1,000 clinical cases of C. auris in the U.S have been confirmed, and knowing what we know about C. Auris, that number is likely to go up. Candida auris is emerging very quickly. So for those countries, or states within the United States where it's prevalent, I would be concerned because you know when you have transmission of an organism, you want to stop that cycle. You don't want this to continue. Candida auris is new, so we need to make people more aware of it. And CDC is doing that along the state labs. But I don't think everyone knows about it as much as they perhaps know about superbugs, like super bacteria that are resistant to antibiotics.
B2 中上級 世界を席巻する薬剤耐性スーパーバグに出会う (Meet the Drug-Resistant Superbug That’s Taking Over the World) 6 0 Summer に公開 2021 年 01 月 14 日 シェア シェア 保存 報告 動画の中の単語