I love that you're rockin' the vintage mug there, my friend.

-Buddy. That is from Season 1.

-Yeah, it really is. -"LNJF."

-Oh, and I thank you so much for being a guest on the show then

and "The Tonight Show," really, and doing this.

It means a lot to me that you came on.

Thank you, buddy. -It's my pleasure.

And I'm always happy to -- to hang with J.F.

-Thank you, bud. Can we talk about the --

-No, James Franco. James Franco.

-[ Laughs ] Of course.

May 12th, on Netflix, the interactive special,

"Unbreakable Kimmy Schmidt: Kimmy vs. the Reverend."

I'm freaking -- -"Kimmy vs. the Rev."

So, all right.

So, you remember these because you're of a certain age,

But there used to be these things called

"choose your own adventure" books, right?

-Right. -And you would read the book,

and at the end of the thing, it would say,

"Okay, do you want to go into the cave,

or do you want to go on to the -- into the river?"

And then you would turn to whatever page it was,

and you would follow that -- that path.

So, this is that, but in the 21st century

with Tina Fey and Robert Carlock writing jokes

and the -- the -- the whole world of Kimmy Schmidt.

And we have additional talents of Daniel Radcliffe...

-No! -...who plays --

who plays Kimmy's fiancé. -[ Laughs ]

And so there's a -- there's a big reveal

in the -- in the whole thing.

And it's -- it's the -- it's the universe

that you have known and loved with "Kimmy and the Reverend,"

but it's -- -Hey, Daddy.

-It's very -- Uh-oh! Special guest star!

-Sorry. Special guest star. -Where's Mom? Do you --

-Special guest star!

-Where's Mom? -Hello!

-Say, "Hi," Winnie. -Hi.

-Tell Jon what you're -- what you're reading.

What are you reading?

-This is not a book. -Yes, it is.

-Coloring -- it's a coloring book.

-Okay, well, you can kind of read it.

It says "Farm Animals." -Okay, I'm working on this one.

I just need to do the background.

-That's really pretty.

That's a -- That's a really pretty cow.

-It's not -- It's a pig.

-Uh. Right, a pig -- that's what I meant.

What did I say?

-But I can show you what's a cow.

-Okay. -That's a cow.

-Eh, that's a lamb. -No.

-Wait, show me -- is there a duck?

-[ Laughs ] -Let me see.

-Is there a duck in there? -What about a chicken?

-I'm gonna see if there's a duck.

-Duck or chicken -- anything with a beak.

-[ Laughs ]

That is a couple of chickens right there.

If I've ever seen a chicken, that's a chicken.

-Just a couple of chickens. Alright.

Bye, chicken. Thank you very much.

-I'll see you later, chicken. -I'm not a chicken!

-I got a chicken.

-She's not a chicken. -Oh.

-It took home schooling just for her to figure that out.

-[ Laughs ] Hey, that's -- that's --

that's trending positive. That's awesome.

-Yeah, we were -- we were nervous for a while.

We go, "Maybe she might be a chicken.

-"Am I a chicken?" -You know what it was?

It was a hypnotist at, like, a county fair.

-For sure. That'll do it.

But maybe you get one of those really talented chickens

that's, like, good at ticktacktoe

or math or something -- well, you never know.

-Do you know that? I mean, dude,

I heard rumors of that chicken in New York City.

-Oh, yeah. -You know him?

-Well, you know who I -- I learned stories

like that about -- was from Hal.

Like, he knew all of those weird, like,

the New York flea circuses and...

-He really did. -...math chickens.

And [scoffs] I mean -- God bless.

-He was such -- he was so New York, Hal Willner.

Wasn't he unbelievable?

-It was the -- that's what I mean.

There's never -- There's -- You know, it's -- it's --

there's -- there's -- there's only a few dedicated weirdos

left in the world... -Yeah.

-...and he was 100% one of them. -I loved -- Yeah, yeah.

I think he might have told me about that --

either him or Zog told me

about the ticktacktoe-playing chicken.

-Yeah. I mean, it was -- -I mean, that again --

-That was like what -- That was what, like,

Times Square was back in the old days.

Like, it was -- you would go there for,

like, peep shows and, like, freak shows.

-But you would gamble against the chicken or no?

-Yeah. You'd bet against the chicken.

And you would always lose.

Or -- Unless you were an idiot, 'cause tick--

-Oh, my God. -You can't lose ticktacktoe

unless you're terrible.

-Hey, Jon, we ask everyone who comes on the show

if they have a charity that they want to highlight

or spotlight or work with or just want to talk about.

And you chose one that I think is just fantastic --

StJude.org.

Man, oh, man.

What's your connection with St. Jude?

-I've -- I've been -- I've probably been working

with St. Jude for a better part of two decades.

I -- My -- I have an uncle that lives out here

who married my mom's sister.

And his best friend was a guy named Tony Thomas,

who is Marlo Thomas' little brother

and who is Danny Thomas' son.

And Danny Thomas started a long, long time ago

an organization called

"St. Jude Children's Research Hospital"

that basically made sure

that any kid that was sick could get care, free of charge.

And not only did he make sure that happened

through donations and endowments

and all this fundraising stuff that you have to do --

they also began

an incredible research facility down in Memphis,

where the organization is centered,

that has increased the curability rate

of so many pediatric diseases and cancers,

and -- and -- and ailments

that were previously thought to be 90% to 100% fatal

are now down in the single digits.

So they've done an amazing job

at not only helping the kids, obviously, get better,

but also providing the -- the framework

for the emotional support of the families.

-Yeah. -Because as you know as,

if your kid ever gets sick,

it's not -- it's not just about them --

it's everybody gets emotionally involved in it.

So it's -- it's an amazing organization.

It's one that I think is great.

I think you've done some work with them, too, in the past.

-Sure. -And they -- they --

they do it all for free.

I mean, that's the other great part of it

is that nobody's making money off of it,

and they're -- they're fully sharing all of their research

with organizations around the world,

and they're considered one of the preeminent ones.

So, they're -- they have a big event coming up on Tuesday

where they're -- they're doing a global streaming situation.

-Oh, great. -I'm sure -- I'm sure

we can throw a link up on there if --

- Absolutely. Done. -So, yeah. So, that's it.

And -- And it's -- it's always been something

I've -- I've been -- I've been a big believer in, and...

-That's great. -...I hope -- I hope people --

people get the word out and -- and donate.

-Anything you guys can give --

anything, even if it's a dollar --

it means a lot.

It goes a long way.

So, please. -Goes a long way.

-StJude.org.

And I want to thank you, Jon Hamm,

for coming on the show, for just being you.

And I just miss you,

and I can't wait to see you in person, buddy.

I really do. I have this -- Hugs can't go away, right?

-No. Here we go! Let's bring it in!

-[ Laughs ] I love you, bud. -Love you, Jimmy.

Good to see you, bud. -Thank you, pal.