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  • We used to think that the brain

  • controlled all our movements,

  • so when you had a spinal cord injury,

  • if you lost that communication between the brain

  • and the spinal cord, there's really nothing you can do

  • unless you regenerate that connection.

  • It turns out, the spinal cord has much more

  • of a sophisticated role than we thought before.

  • We can stimulate the neural networks in the spinal cord.

  • We can help the spinal cord relearn

  • how to do things it was able to do before the injury.

  • I was supposed to have been an individual

  • that was gonna live and die from this chair.

  • I mean, with the epidural stimulator,

  • it's so close to the point of just moving this leg.

  • You're growing the ability to recovery.

  • I really think that it's gonna give me

  • the availability to get out of this chair.

  • Growing up, we started out with go karts,

  • and then we got into bicycles and everything.

  • My grandpa took me to my first Supercross race.

  • Seeing that, it instilled me with this want

  • that that's what I wanted to do.

  • My career was at the point where I was amateur pro.

  • It was a couple races, and then I had my pro points,

  • where then I could race the stuff that you see on TV.

  • I went out and I was testin' a new motorcycle

  • that I had just got.

  • And it was like a hundred foot jump.

  • Right off the face of that jump,

  • I remember the motor just locked up.

  • It had me pinned, and then it just ,

  • and just tumble, tumble, tumblin'.

  • Some people came up to me and were like, you okay?

  • And I'm like, no, I don't think so.

  • Can you get up?

  • I was like, no.

  • You're paralyzed from the waist down.

  • You're a complete injury.

  • You can't feel anything.

  • You're not gonna regain any mobility, any function.

  • From here on out you're gonna have to have daily care,

  • more than likely.

  • You're gonna live from a wheelchair.

  • That was a lot to swallow.

  • Basically how I took it was that from that point on,

  • my life was starting to end,

  • versus it continuing to be an adventure.

  • That was how it felt to me.

  • When I got that prognosis,

  • the first thing I went to was looking at centers

  • that offered rehab and locomotor training,

  • and which were the top ones.

  • That was where I kinda heard through the grapevine

  • that they had a guy in Louisville

  • that was going through the procedure

  • for the epidural stimulator,

  • and they were seeing some very interesting things happen.

  • Left toe up.

  • We were doing a series of experiment.

  • We implanted the individual with the epidural stimulator.

  • He was laying down and he, on his own,

  • tried to move voluntarily.

  • He tried to move his toes, and he wiggled his toe.

  • And I said, holy S***.

  • We did not anticipate that.

  • We tested it, the stimulator off, and they cannot move.

  • When you turn the stimulator on,

  • they're able to move.

  • This dude's got a switch that just makes him normal.

  • That's how it was making me perceive it.

  • Our whole theory about how

  • the motor system works was challenged.

  • So the traditional way of thinking

  • about a spinal cord injury is that the brain

  • is the primary controller of movement and function,

  • but it turns out the spinal circuitry

  • is as smart as the brain.

  • It can learn, it can remember, it can forget,

  • and it can make decisions.

  • How we actually walk is this circuitry already has in it

  • the ability to generate patterns to walk.

  • As devastating as a spinal cord injury is,

  • that circuitry still has the ability to do that,

  • but it loses what we would call state of excitability.

  • So the epidural stimulator is

  • an off-the-shelf pain stimulator

  • that's used in people for pain.

  • It has a lead that's placed in the lower spinal cord,

  • and it generates an electric field.

  • So the stimulator actually helps those neurons

  • that are still viable, that are still alive,

  • to be able to function like they did before.

  • It's five days a week, two sessions a day.

  • I started with a toe.

  • And then it started with an ankle,

  • and then it started with a leg.

  • 12 sessions in I got my first holt

  • of independence in standing.

  • It's gotten to the point now

  • where it just happens naturally.

  • I just lean forward on my walker

  • and think that I wanna stand, and I stand,

  • and my legs, they hold me.

  • When you immediately turn it on,

  • you don't really notice, but once you get a couple volts up,

  • it's like you feel the body charged and ready.

  • When you're trying, you feel that go through your head,

  • from your brain, down your spine, to that leg.

  • Give 'em some body weight support, keep them balanced,

  • and then people move their legs in a walking-like pattern.

  • That sends the right information about walking

  • back to the spinal cord, which it's expecting.

  • And because the spinal cord's smart

  • and it can learn, it starts relearning how to walk again

  • with that information and the person thinking about walking.

  • And over time, in some people,

  • they're able to step independently,

  • and in two people, walk completely independently

  • from physical assistance,

  • but just use a walker or canes to walk over ground.

  • The biggest thing is feeling it,

  • because after injury, you feel nothing.

  • And when you execute those movements, you feel them.

  • It's gonna be a really quick move.

  • Shift, and then load.

  • There you go.

  • I exploded a vertebrae.

  • What is known before all this

  • is there's no way, no how that I'd ever be able

  • to take a step again, but that's wrong.

  • The next step really needs to be to design one

  • that is very specific for the shoes.

  • So the device that we envision is akin to a smartphone.

  • It can be voice activated.

  • Says, okay, I wanna stand now.

  • So you have your stand program.

  • I wanna walk now, you have your walk program.

  • It has closed loop feedback.

  • The blood pressure is monitored.

  • Do all of this as autonomously as possible.

  • This is not a cure.

  • There's not going to be a silver bullet for this.

  • There's not anywhere, I think in the near horizon

  • where we're gonna completely regenerate

  • the spinal cord after an injury.

  • But if we can make an incremental change in function,

  • it improves their participation in life.

  • One of the things that hits you

  • when you're in the hospital,

  • am I ever gonna get married?

  • Am I gonna have kids?

  • And at this point, I'm married.

  • And the epidural stimulator program

  • gave me the ability to stand at my wedding.

  • As soon as she started walking down the aisle,

  • the emotion just hit me.

  • I don't really cry, but man, I was ballin'.

  • Even getting to dance with my mom.

  • That was so awesome.

  • And I feel so close to the kids thing.

  • I know it's comin'.

We used to think that the brain

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この偶然の治療が麻痺を逆転させている (This Accidental Treatment Is Reversing Paralysis)

  • 3 1
    林宜悉 に公開 2021 年 01 月 14 日
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