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  • Hi good afternoon everyone and thanks for joining us.

  • My name is Rebecca gold

  • and I'm working at CDC on the COVID-19 response.

  • I'd like to introduce you to doctor jay butler, CDCs

  • department director for infectious diseases.

  • He'll be giving you an up date about what's happening

  • currently and also be available to answer some

  • questions.

  • Doctor butler.

  • SPEAKER: All right thank you Rebecca.

  • Good afternoon or good morning everyone depending on

  • where you are.

  • So let's start with a situation up date.

  • I think everybody's become aware of the spread of the

  • COVID-19 virus since it's original

  • emergence in Wuhan China in December of this year.

  • Over the past two and a half months the epidemic has

  • progressed.

  • The first two months really China was the center of the

  • outbreak and Wuhan province in central China in

  • particular was impacted.

  • As of now there have been over 80 confirmed cases in

  • China and over 3,000 deaths.

  • However as of about a week ago the number of cases

  • occurring outside of China began to exceed the number

  • of cases occurring within China.

  • Both the cause of

  • spread of the virus around the world and also because

  • the number of new cases in China has gun to decline.

  • Outside of China there's been cases reported now from

  • some 85 nations.

  • Of course including the United States.

  • Overall over 10,000 cases have

  • been reported from outside of China.

  • The hot spots currently are in the republic of south

  • Korea, also a number of cases have been reported with

  • community transmission in

  • Japan and then the two other regional hot spots are

  • Europe, particularly with cases I

  • aminating out of outbreaks that were occurring in

  • communities in northern Italy and also the eastern

  • Mediterranean region with cases I aminating from I ran

  • particularly the talon of cove.

  • Here in the United States the number of cases has

  • increased over the past several days.

  • With reports of cases from 13 different states.

  • The cases where there's been community transmission

  • have primarily been on the west coast but not solely on

  • the west coastthism is a very fluid situation and as

  • testing becomes available through an increasing number

  • of state labs as well as in the near future commercial

  • laboratories we anticipate that the epidemic will

  • continue to be

  • recognized and spread will be better defined.

  • The issues that I think are of greatest concern to us

  • right now are spread to people who are more vulnerable

  • for severe illness.

  • There has been cases in a long term care facility in

  • the Seattle area where there have been eight deaths

  • associated with infection.

  • The illness

  • itself is one that's primarily a respiratory illness.

  • As we know more about the manifestations.

  • We also know that most people about 80 percent have

  • relatively mild illness although it may involve

  • pneumonia.

  • The majority of people actually do recover but there's

  • still 20 percent that have more severe illness that may

  • require medical care or hospitalization.

  • Mortality is an area of great interest to us because as

  • we assess the impact of the epidemic and what are the

  • appropriate interventions and considering both the

  • risks and benefits we want to know how transmissible it

  • is and how surear is the illnessment you've probably

  • heard reports in the illness saying it's 200 times more

  • fatal than influenza.

  • I think that's probably a biased statement because we

  • have less visibility on the milder cases.

  • Our estimates suggest that it's probably less than one

  • percent but keep in mind if this is a virus that is

  • capable of infecting the vast majority of people that's

  • still a very very significant number.

  • The people at highest risk are those who are elderly

  • and also those with underlying illnesses particularly

  • chronic heart and lung disease as well as diabetes.

  • The interventions to date have focused on how we could

  • delay the virus in the country

  • and limit it's spread.

  • Those are interventions designed to buy us more time to

  • be able to be prepared for the entry of the virus and

  • as we move into a time of progresses of mitigation,

  • recognizing that community spread is occurring in some

  • locations again the focus is on how do we spread the

  • impact of the epidemic over as long a period as

  • possible so that businesses can remain open as much as

  • possible and so that the impact on health care is not

  • going to be overwhelming if it can be at all avoided.

  • This would also give us more time to develop effective

  • antiviral

  • medications and ultimately to have a protected and

  • preventive vaccine.

  • Even though it may be possible to have a vaccine that's

  • ready to enter human trials over the next two to three

  • months because of what's required to show that's

  • vaccine would be safe as well as effective I think it's

  • unlikely that we'll have a vaccine for the general

  • population in less than 18 months.

  • There is also a wealth of information that's

  • available on the CDC website that I wanted to call

  • attention to.

  • There are guidelines specifically focused on businesses

  • how to be prepared.

  • I think the important take homes from that are issues

  • related to HR and making sure that em plies

  • are able to stay home if they are sick.

  • That will be to your benefit as well as your work

  • forces benefit as well as your customers.

  • And then also particularly if you're in the public

  • service sector being able to provide hand hygiene

  • products whether that be reminding people to wash their

  • hands or providing jells to san ties hands as much as

  • possible those would be things that we would recommend.

  • Guidelines on large events.

  • Also recommended precautions

  • preventing the spread in election polling locations.

  • Prevention of spread in

  • communities, interim guidance on public health

  • communications for communities.

  • Additional resources for health care facilities.

  • Strategies for optimizing the

  • supply of N95 respirators which I think is of

  • particular interest to health care providers in the

  • health care industry.

  • Strategy taz prevent spread in long term care

  • facilities which I think is an area of keen interest

  • given the concentration of high risk individuals in

  • these facilities.

  • General guidance for health care facilities.

  • Also guidance for institutes of higher education

  • including specific guidelines for

  • students wanting to study abroad.

  • There's also some household readiness guidance and

  • some documents on combating sigma and also frequently

  • asked questions for children.

  • I think I will stop at that point and I understand

  • there is a cue of questions

  • already so I will turn it back over to Rebecca.

  • SPEAKER: I am here.

  • First question we got in advance was we heard there's

  • on going research on the life span of the virus.

  • Could that change the cleaning requirements because

  • right now the website says there there's no need for

  • deep cleaning or extra cleaning measures.

  • Is that going to change?

  • SPEAKER: This is a broad answer to many questions.

  • We're still learning this virus.

  • What we know about it so far which suggests that the

  • routinely touched surfaces can be cleaned with cleaners

  • that are typically used.

  • These would be using products according to the

  • directions on the label.

  • We do not have recommendations for specific PPE for

  • prevention of infection of people who are doing the

  • cleaning but of course the PPE whether that be gloves

  • or eye protection that are appropriate for the cleaning

  • solution itself is important to continue.

  • The survival of the virus on surfaces is one of great

  • interest to us right now the epidemiology as well as

  • what we know about other corona virus's suggest that

  • it's probably spread through respiratory droplets

  • meaning droplets that are not air born but may be

  • projected during coughing or sneezing.

  • But there is some experience particularly with the sars

  • virus that suggests that surfaces can become

  • contaminated and that the survival of the virus could

  • be for a period of minutes or hours and that it could

  • be potentially

  • transferred usually through hand contact.

  • That's one of the reasons why we have such a

  • concentration on hand hygiene as well as break the very

  • difficult habit of putting your hands to your face.

  • There have been a number of projects assessing the

  • viability of the virus on surfaces and I think that

  • backs the current recommendation.

  • However it's important to recognize that some of this

  • research has really focused on what are the outer

  • limits under absolutely ideal conditions which may be

  • unlikely to achieve in real life.

  • So if you hear of contaminated surface and virus being

  • recovered for days that may indeed be possible.

  • What we don't really have evidence for is that that's a

  • significant mode of transmission.

  • Questions have been raised about whether or not mail

  • and packages could become contaminated.

  • Also question

  • business money.

  • You know right now the epidemiology does not point

  • toward that particularly as we talk about the mail.

  • We would've seen more I think met static

  • infections very early in the epidemic given that China

  • is very interconnected with the rest of the world and

  • is a major exporter of products in a number of

  • different goods.

  • The epidemiology of the spread out from China has also

  • been exclusively, travel to China, exposure to someone

  • who issismmatic and then exposing other people after

  • return.

  • In terms of specific products it's kind of the routine

  • things in terms of sodium hypo chloride meaning bleach

  • type products or alcohol wipes.

  • SPEAKER: Great thank you.

  • Do we know if recovered patients are still capable of

  • spreading the disease?

  • SPEAKER: It appears the people who are most infectious

  • are people who are actively ill.

  • Persons who are coughing and sneezing of course are

  • having a harder time controlling their secretions and

  • more likely to transmit it to people around them.

  • There is some evidence that people are shedding the

  • virus shortly before the on set of symptoms and there

  • is also evidence of asymptomatic infection.

  • At this point in time we have very limited evidence

  • that those asymptomatically infected people are playing

  • a significant role in transmission.

  • But we are very concerned about that possibility and we

  • continue to monitor it very closely and continue to

  • collect data.

  • For people who have had documented COVID-19 infection

  • our current strategy is to have those people isolate

  • whether it's in a health care facility or self

  • isolation at home until there has been two negative

  • tests consecutive respiratory specimens and this is

  • usually a swab up the nose and also in the throat

  • through the mouth and that both of

  • those tests would be negative on two different

  • occasions at least 24 hours apart.

  • There have been some isolated incidences of tests

  • collected later that were positive showing a very low

  • viral load and at this point in time we are still

  • determining what

  • the significance of those tests are.

  • The PCR is a very sensitive assay.

  • Particularly at lower viral loads.

  • Detecting not so much a proven viable virus as

  • certain pieces of the genetic material of the virus in

  • that genetic material certainly could still be present

  • even after the active infection is cleared.

  • SPEAKER: What are the other things we should be doing

  • to prevent the spread of COVID-19 that are different

  • from what we're already doing to limit the spread of

  • flu.

  • For example we know to wash our hands, general

  • sanitation.

  • What additionally should

  • we be thinking about doing to prevents COVID-19 spread.

  • SPEAKER: Rebecca thanks for bringing up flu because

  • first of all although this may seem a little counter

  • intuitive it's important to get a flu vaccine.

  • The on going assessment of the flu vaccine effect

  • ofness this year is about 50 percent.

  • That is a significant 50 percent so if you can reduce

  • your risk of flu by half that's a good

  • intervention.

  • It also then provides less protection against flu not

  • only can protect your health but can make the health

  • care system more robust by avoiding a big in flux of

  • people with influenza.

  • The influenza activity right now is at a peek.

  • Even

  • though a lot of the focus has been object COVID this

  • has been a bad flu year.

  • We started out with influenza B.

  • As that was declining influenza AHb one N one, the

  • descendants of the 2009 pan tellic strain has had a

  • come back.

  • This second peak is actually much worse than the first.

  • There have been tens of thousands of people who

  • have died of influenza this year.

  • Those are in many ways those are preventable deaths

  • through vaccination.

  • Other things that can be done.

  • You've already mentioned

  • hand hygiene.

  • It also comes down to issues like avoiding people who

  • are sick.

  • We more and more are doing what we call the pandemic

  • handshake around here which is bumping of elbows.

  • People may have also seen some of the news in France

  • the

  • government has suggested that people sus spend the

  • practice of the kisses on the cheeks to be able to

  • limit that amount of contact.

  • Lastly for people who are at highest risk of disease

  • they may want to consider whether or not they're

  • attending mass gatherings.

  • There are in the works some other guidelines from the

  • CDC including -- and a number of those organizations

  • have already taken steps to minimize the amount of face

  • to face contact as well as public contact during

  • services and other religious

  • activities.

  • SPEAKER: Thanks doctor butler.

  • Can you please clarify whether the CDC is

  • recommending self isolation after returning from any

  • country with a level three

  • travel advisory or just China.

  • SPEAKER: This is a good question because it delays the

  • fluidity of this situation in how the recommendations

  • are transitioning to the global aspects of the

  • outbreak.

  • I think the short answer is keep an eye on the

  • cross-examination DC website.

  • Currently

  • the recommendations for what we call level three

  • countries meaning we would recommend for health reasons

  • to delay all nonessential travel are continue for China

  • but in the past week have now also included south Korea

  • Italy and I are an.

  • There is a level two recommendation for Japan where we

  • recommend for people who are at highest risk or most

  • vulnerable also recur travel.

  • SPEAKER: Are peal still being screened at the

  • airports?

  • Are they screening for flights that are returning from

  • south Korea or Italy and are those people being told

  • to self monitor and/or self isolate?

  • SPEAKER: National level the screening is still for the

  • flights arriving from China.

  • The steps being taken to address limiting importation

  • from other countries are

  • evolving fairly quickly.

  • We recognize that's whole process of traveler

  • restrictions is a cost benefit process.

  • We want to minimize impact on travel and personal

  • freedoms as much as possible.

  • Also recognizing that there is a significant economic

  • impact as well as personal impact on limitations of

  • travel.

  • The caveat in that is that some of the states have that

  • have not yet had any community transmission have

  • encouraged self isolation or self quarantine actually

  • for people who are returning

  • from these high risk countries.

  • It's important to recognize how the public health in

  • the country works.

  • Often times the implementation of public health is at

  • the state of local level.

  • SPEAKER: What does CDC recommend as a good source of

  • information to help companies and businesses decide

  • whether they should isolate or quarantine individual

  • who's have traveled or possibly been exposed to either

  • flu or COVID-19?

  • SPEAKER: I certainly use that as a chance to plug the

  • CDC website.

  • CDC dot gov'

  • back slash corona virus should take you there.

  • There's a whole wealth of

  • information.

  • And I think I mentioned earlier some of the guidance

  • for businesses.

  • If you have comments on that we would actually welcome

  • that.

  • I wanted to make sure people were aware that we want to

  • make sure we're providing guidance that is practicable

  • and as helpful as possible.

  • Our goal is to have science and evidence based

  • guidelines and the science is quickly evolving and may

  • be subject to change.

  • Keep that site book marked.

  • Keep an eye on what some of the newer publications that

  • show up on that website are.

  • SPEAKER: What's the best practice for a company should

  • an employee report flu like

  • symptoms after travel.

  • Should they close the office and have the staff work

  • from home until lab results come back.

  • If a family member reports symptoms what's a

  • companies recommended course of action.

  • SPEAKER: That's a really good question.

  • The first and most important step is to make sure that

  • anybody who is sick goes home.

  • Or if they're seriously I tell contact their health

  • care provider.

  • You want to be able to separate those who are sick from

  • those who are not to minimize transmission.

  • The words I used were contact a health care provider.

  • We don't want people to just show up in the clinic and

  • potentially

  • sit there for a couple of hours coughing.

  • We want them to be able to have an interaction with a

  • health care provider so they can be advised of the best

  • way to come see a health care provider if that's

  • necessary and so appropriate infection control measures

  • can be in place.

  • If you have an employee who's confirmed to have

  • COVID-19 I want to just remind everybody that there are

  • issues related to personal health care information and

  • so be sensitive to that.

  • Your HR offices may be able to provide you some

  • guidance on that.

  • And in terms of whether or not that means

  • businesses should curtail activities or potentially

  • close those are really critical

  • questions that have to be made on a case by case basis.

  • So that's where it's very important to contact your

  • state or local health department for on going advice

  • and also you can contact CDC as well.

  • But do keep in mind that you have those local resources

  • as well.

  • SPEAKER: Okay.

  • Is there an infection matrix or any sort of guiding

  • numbers of

  • infected people in the population that would indicate a

  • recommendation to maybe close

  • scullers cancel public events?

  • SPEAKER: Yeah another really good question.

  • Ultimately whether an event is canceled or not depends

  • on the situation and ultimately will be determined by

  • the state or local health authorities.

  • That's where the legal jurisdiction to be able to do

  • that sort of thing lies.

  • The role of CDC in that is to be able to provide

  • guidance to the state and local authorities and to help

  • them with some of the preparedness activities to help

  • them be able to do that.

  • It really comes down to the specifics yesterday CDC

  • posted mass gathering guidance on our website.

  • CDC does not have legal authority to cancel local

  • events or to close schools and that would not be

  • appropriate anyway because these are decisions that

  • really need to be made locally.

  • Ultimately we may see that this epidemic impacts all

  • parts of the country but right now it is not all parts

  • of the country and it will be not all over the country

  • all at once most likely.

  • In some ways it's kind of like the flu.

  • Continues to wane as it continues to

  • increase in other areas.

  • SPEAKER: Thank you if we're travsee someone with

  • symptoms who should we report that to?

  • SPEAKER: It really depends on the situation that

  • you're in but traveling is a very broad point whether

  • we're talking about airports or on board a ship or on

  • an air plane.

  • Probably the easiest one if you're on a cruise ship

  • would be to alert the medical staff on board the ships.

  • I'm sure if anyones traveled recently you've seen a lot

  • of people wearing masks.

  • Anticipate that's something that people may be

  • wondering about because that's a question we get a lot.

  • The CDC currently does not recommend use of masks in

  • community settings.

  • Because of really limited data that suggests there's

  • any benefit of that.

  • If someone wants to wear a mask you know I think the

  • biggest concern right side two fold.

  • One is just the limited supply of masks that are

  • available but second of all just anecdotal observation

  • by one jay butler is I just noticed how many people are

  • wearing masks keep reaching up to their face to adjust

  • it.

  • Just two days ago in an airport I watched someone on

  • the escalator who continually took their hand from the

  • hand rail and took it to their

  • face to adjust their mask.

  • It's conceivable that they actually could increase your

  • risk of the in exposed to respiratory virus possibly

  • including the COVID-19 virus.

  • SPEAKER: Thanks.

  • I got the question that originally we were advised to

  • screen for travel for the past 14 days and we're now

  • seeing for up to 27 days.

  • Which is

  • correct?

  • SPEAKER: The vast majority of cases where there is a

  • discreet exposure fall in the range of about four to

  • seven days.

  • The outer limits are mostly in the range of two to 14

  • days.

  • Just the observation of the various reports and

  • interpretation of what's

  • being published in the scientific literature is those

  • instances of the outliers that are much larger than 14

  • days are mostly in settings where one there's a lot of

  • community transmission and it may be very difficult to

  • isolate just where exposure occurred and two is in

  • situations where the information for the possible

  • exposure is being obtained through things like medical

  • records review which I can say as a physician we don't

  • document in the medical record everywhere someone has

  • been and every sick person they've been around in the

  • last month.

  • I think that's a very undependable source of

  • information.

  • So at this point in time I feel like the two to 14 days

  • is going to cover the vast majority of cases when we're

  • looking at what is the most likely incubation period.

  • SPEAKER: Okay and I know that your schedule is

  • requiring us to actually wrap this up early but for the

  • last question I just wanted to ask what's CDCs guidance

  • on banning travel to specific countries.

  • SPEAKER: Again the approach to this is to avoid

  • limiting movement as much as possible.

  • But striking that balance between what are the risks

  • and benefits of

  • limiting travel.

  • This is an area where we continue to evolve very

  • quickly and again the level three guidelines which

  • really do recommend delaying all nonessential travel

  • focus on China, south Korea, Iran and Italy.

  • MALE SPEAKER: Thank you so much and thank you

  • everybody for joining our call.

  • If we

  • didn't get to your question please check our website.

  • We have a feeling the answer will be there and keep

  • your questions coming and we will try to answer them

  • and thank

  • you for your patience and for your attendance today.

Hi good afternoon everyone and thanks for joining us.

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