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  • The HeartMate II was first approved in 2008 as bridge to transplantation.

  • It was developed as a new generation of the HeartMate device that has been around since

  • mid 1990s. They thought about creating a more durable, smaller device that will last longer

  • and will be available to more people in terms of body size. It was approved as destination

  • therapy in 2010.

  • Destination therapy means that patients that otherwise are not a transplant candidate because

  • either of the age, or other comorbid conditions have the ability of having an improved quality

  • of life by receiving this device called Left Ventricular Assist device, HeartMate II as

  • the last option for advanced and stage heart failure.

  • Heart transplantation, while the gold standard for treating severe end-stage heart failure,

  • is not the answer for many, even most patients with end-stage severe heart failure. The ability

  • in certain Left Ventricular Assist devices for this disease is going to have more of

  • an impact population-wise in the United States than heart transplantation has.

  • The device works in conjunction with the heart is implanted via open heart surgery. It’s

  • connected to the heart via tube. And then it basically sucks the blood out of the heart

  • and it pushes it into the circulation via another tube that’s connected to the aorta,

  • which is the big blood vessel that travels through the body and distributes the blood

  • to the vital organs.

  • It’s been pre-consistently shown that the overwhelmingly majority of patients go into

  • surgery in class four or class three heart failure, and come out in class one or class

  • two heart failure. But most people with heart failure are limited in what they can do many

  • times to the point where it can’t even engage in the activities of daily living.

  • Now individuals can reengage in life and can do a lot of the things that they weren’t

  • able to do typically for many years.

  • They only have mild limitation with extreme activities, but a lot of them can return to

  • work, can return to doing their daily activities and their hobbies. They can go shopping, go

  • to the movies. We had somebody that roofed their entire house. We currently have somebody

  • out in the community that’s farming for the time with the device.

  • The device has one single limitation; you cannot go swimming with the device. You can,

  • however, fish from the shore or in the waters. The device is completely quiet, so it doesn’t

  • interfere with your daily living activities. Overall, the device weighs less than a pound.

  • Most of the people won’t feel it; it doesn’t interfere with their activities and it is

  • so small and it can be so well hidden, that we have people that actually get married with

  • the device.

  • We don’t know how long theyre going to last. Technology is always changing. We know

  • there are very durable, much more durable than the first generation devices.

  • The longest device in the United States that has lasted has been about six years since

  • the device is pretty new. However, this device can be replaced with a usually easy operation.

  • There’s no limitation into how many devices you place. Obviously, your body has to be

  • in good shape.

  • A lot of the patients that have been younger patients have chosen not to pursue transplantation

  • and continue to live on these devices because of limited medications that they have to take.

  • Less follow-up, less invasive procedures, and the ability of changing this device and

  • still receiving the transplantation at the back and if it’s necessary. Therefore, having

  • the higher chance of expanding their life expectancy.

  • A lot of times what were finding is that individuals who may not have been candidates

  • for heart transplantation may become candidates for transplant and in a certain number of

  • individuals, there may also be recovery. There are a minority of patients out there who do

  • seem to get recovery of heart function after a period of time on the Left Ventricular Assist

  • device.

  • It opens the door for improving quality of life to a lot of local patients that otherwise

  • they would have no hope.

  • The results from Left Ventricular Assist device have been improving incrementally, and we

  • may see the point where these devices may rival the results that were seeing with

  • heart transplantation, which to this day remains a gold standard.

  • We, as medical community, are able to provide patients here in Nebraska with the therapies

  • that otherwise they would have had to travel long ways. I think that is a great achievement

  • for the community and I’m proud to be part of the team at Nebraska Medical Center.

The HeartMate II was first approved in 2008 as bridge to transplantation.

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左室補助装置(LVAD)を目的地治療として - ネブラスカ医療センター (Left Ventricular Assist Device (LVAD) As Destination Therapy - The Nebraska Medical Center)

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    Ting Huang に公開 2021 年 01 月 14 日
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