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  • So now let’s take a closer look at dopamine.

  • Dopamine is a naturally occurring catecholamine.

  • It has direct alpha and beta adrenergic effects depending on the dose.

  • Now when a medium dose is given, like 5-10 mcg per kg per minute, dopamine acts directly

  • on beta1 receptors which causes increased myocardial contractility and increased heart

  • rate.

  • When used in doses greater than 10 mcg per kg per minute alpha receptors are stimulated,

  • which results in an increase in systemic vascular resistance, in other words vasoconstriction.

  • Dopamine can be a very effective drug in treating hypotension with signs and symptoms of shock.

  • Dopamine is typically used as a second line drug for symptomatic bradycardia after atropine.

  • Now dopamine may cause tachyarrhythmias and excessive vasoconstriction and should be used

  • with caution in patients who are suffering from cardiogenic shock with associated symptoms

  • of Congestive Heart Failure.

  • Now it’s important to correct hypovolemia with volume replacement before we initiate

  • dopamine therapy.

  • The adult dosage for dopamine should be administered via IV and it’s most common infusion rate

  • is 2 to 20 mcg per kg per minute.

  • We want to be sure to titrate the dosage and drip rate to patient’s response slowly and

  • carefully.

So now let’s take a closer look at dopamine.

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B2 中上級

ドーパミン(ACLS薬理学 (Dopamine (ACLS Pharmacology))

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    呂家賢 に公開 2021 年 01 月 14 日
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