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  • Humans have long pursued the Fountain of Youth and with the wide-ranging benefits of reducing disease and enabling a longer, healthier life, reversing the causes of aging is a major focus of much medical research.

  • Normally, the process of aging in the human body starts at middle age around 45.

  • The process and its effects depend on both, the genetic as well as environmental factors.

  • Aging causes some amount of reduction in the rate of human cell multiplication

  • and also causes some of the cells to function inappropriately.

  • Ageing is considered a one-way street, but researchers at Harvard University have shown that some aspects can be reversed.

  • Researchers say that they've been able to reverse the aging process in mice,

  • using a chemical that in one week made two-year-old mice tissue resemble tissue of six-month-old mice.

  • In human years, that's as if a 60-year-old's cells became more like the cells of a 20-year-old.

  • The researchers have managed to reverse the effects

  • of aging in mice using an approach that restores communication between a cell's mitochondria and nucleus.

  • Mitochondria are the power supply within the cell,

  • generating the chemical energy required for key biological functions.

  • When communication breaks down between mitochondria and the nucleus,

  • which is the cell's control center, the effects of aging accelerate.

  • The study found that by restoring this molecular communication,

  • aging could not only be slowed, but could be reversed.

  • Responsible for this communication breakdown is a decline of the chemical NAD.

  • This chemical reduces in the body as we age.

  • By increasing amounts of a compound used by the cell to produce NAD,

  • the researchers found that they could quickly repair mitochondrial function.

  • And that led to the radical reversal in the ageing of the mice.

  • They had more energy, their muscles were as though they'd be exercising

  • and it was able to mimic the benefits of diet and exercise just within a week.

  • Researchers say that the diseases they have come to expect of old age have been drastically reversed in mice.

  • Even the younger mice showed benefits from the compound,

  • making them "supercharged" above normal.

  • The researchers say a "magic pill" that reverses ageing is several years away,

  • partially due to the cost of the compound, which would be about $50,000 a day for a human.

  • Reversing aging isn't just to make people live until they are 200 or 300,

  • the goal is to keep people healthier for longer and keep them from getting diseases of aging.

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Humans have long pursued the Fountain of Youth and with the wide-ranging benefits of reducing disease and enabling a longer, healthier life, reversing the causes of aging is a major focus of much medical research.

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B1 中級

老化は逆転する可能性があるのか? (Could Aging Be Reversed?)

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    Precious Annie Liao に公開 2021 年 01 月 14 日
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