字幕表 動画を再生する 英語字幕をプリント I used to drink a lot of coffee on my hand, shook even more than they do now. About 12 years ago, maybe more now. I went to China for a week, and when I left I was really addicted to coffee. And when I came back, I was found myself addicted to green tea. And since then I've drunk nearly entirely green tea, and very rarely do I drink coffee. And the result is that if I do have some coffee, I feel hyper for the rest of the day and I really can't sleep well. It's a molecule I know. On DDE, I can just about recognized its structure together. Some carbons, carbons got nitrogen, oxygen, hydrogen, scattering atoms everywhere. If I just saw it is a random molecule, I would probably recognize it because you usually see it on people's coffee cups and things like that. So there's quite a good him. This is capping. If you've never had coffee before, then people do get some stimulation from it. There's no doubt about that's been proven. It can help making a bit more alert and feel bit more vital for a for a few minutes. If you have too much. Of course, lethal dose of coffee is about 80 cups a day, so do not approach that at all. I have read the theory, and I don't know if this is correct that if you take coffee or and some other caffeinated drink, it's a regular time each day. Then your body starts making the antidote to the caffeine before you get the coffee time. So if you have coffee at 10 30 in the morning round about 10 o'clock, your body starts making this antidote. So you've tend to feel really quite in need of the caffeine just to get you back to normal state. So this is about six cups of coffee in here. We're just gonna cool that dying. But on the other hand, if you're suddenly given coffee at a time when you're not expecting it, then your body hasn't gots ready to receive this dose of caffeine, and it has a much bigger effect than you expect. And so it may be not so much that people are addicted to coffee, but they are counteracting the negative effects of what's in their body. Caffeine is very soluble in hot. There's much, much less, 30 times less soluble temperature, Walter. So we're gonna cool it down. So it's like soluble in water. Thank you. Drinking tea and coffee is very important in science in the UK and in many labs, people meet together every day to drink tea and coffee. And some of the best ideas can grew up over tea and coffee. Because when people are relaxed, suddenly clever ideas come in their head. An unexpected side effect of caffeine is its role in science, not directly, but in many labs. Many departments like this one that noting him. The scientists meet together once or perhaps twice a day to drink coffee. I'm quite often they have really good ideas, the caffeine's or relax system on when they're not thinking really hard. Suddenly, a good idea comes into their head. In fact, at the Laboratory of Molecular Biology in Cambridge, which is one I think 14 Nobel Prizes there was a rule. Perhaps there still is that if people are discussing in the coffee room, it's not allowed to close in case there just about to get a good idea. And if the coffee room closes, it may be lost forever, so you never know. If you sit a long time drinking coffee, you might win the Nobel Prize. Water water's more dense than Ethan State, so it sinks to the bottom. They're not admissible. Restraining off that button black male with water because it goes down, you're seeing the top layer is actually fairly clear. So the caffeine now hopefully is in that top, right? Um, this this really boom, boom, boom, But flask, there's still some water in the last eight. So we're gonna use is a drying agent. Magnesium sulfate have always known is Epsom salts. Students often ask me, How do you know how much magnesium sulphate It's a drawing. The answer is when it goes white and fluffy. So it's quite a lot of water, in a sense, Claridges and clump together. So it's probably more when you get that sort of snow storm effect. Just let that dry for a moment. Filter off. This is so what we have here is our caffeine. So the reds here do no oxygen. You've got carbon atoms represented by the black. These smaller white ones are hard shin. And then the blue ones here, which you've got four or nitrogen, so it's kind of the most common elements that make up so many aromatics. Organic molecules. I tried to find a a mug with a caffeine molecule and had to go back to the parent table, but what we had sent in boy, one of our viewers. Um, this gentleman here is clearly a fan off period videos, and he's there enjoying a video of Martin with his broom in hand. But he also including his E mail to US tattoo that he's got, as you can see, that molecule of coffee. So it's clearly a much more devoted fan to the molecule than I am. I just prefer drinking it rather than thinking on myself. It's an hour. Caffeine's in the last eight solution on. We're not gonna remove the last type from it. So you put one of these only is called check clips. Dr. Keck sadly died last year, but very handy clip that bears his name will go on for many, many years to come. No need to card ice cases, cowboy approach time, Dick. Hey, we got some solid safe to use that to condense the last eight so it doesn't go down the drains or into the atmosphere. Okay, so what we're doing is we're lowering the pressure in the system, so that means that alone's boiling point. We're loing boiling point wreath. Alas, it tight. So in here, we've got the last type very low pressure in here. Currently around 90 million bars on that solvent is evaporating. It's coming up here, and it's condensing on this very cold, hard, ice cold finger. Here you can see it coming down and being collected in the flask below. So what we want is to remove all of that solvent. Just leave what was in Seoul. I hope we'll have something that I don't think it's going very much because it was only six cups coffee, but there should be 20 or 30 milligrams, maybe a little bit more for lucky. So what do you think about someone doing themselves with a caffeine molecule? It's certainly a level of geekdom that I have not subscribe to, but I commend him for his devotion to this particular molecule. Well, that's about to change because we've been sent something which I'm giving you is a gift. This this was sent to periodic video really well. They seize. Absolutely incredible. Oh, my gosh. So we've got rid of most of the eighth. Last tight. Now, just last few dregs coming off. You see that? We've got a fairly light yellow Parajuli. Some of the colors come through from the coffee. So there we go caffeine. Now, if we were really good chemist, we re crystallized like it's a nice white crystals on. What we're gonna do is just gonna put this on a high vacuum system to get the very last traces of ether last. This is absolutely gorgeous. I've got a caffeine molecule on a chain. It's a necklace, evidently, but its so called what is this owner was made off. I absolutely adore. This is it's incredible. And it's so caress its allies. Caffeine. It's so sweet. It's so cute. And I love it. But you just you just send people who adorn themselves with Cap. Yeah, I know. I take it back now than I look like a complete idiot at today. There's a difference between getting inked permanently and being able to take it on and off. I'm gonna wear this because I I'm going to the Webby Awards. Um and I'm gonna wear this. I'm definitely gonna wear this on the night. It's gonna be amazing. I had planned on wearing something else, but no, I'm definitely gonna take this to New York. And I'm gonna wear it for the Webby Awards because it's just it's absolutely immense. Love it. Thank you to whoever made this. That's been on the five minutes. So take this off now what? 0 100 milligram. So six cups of coffee has 100 milligrams of caffeine 17 or so milligrams in a cup of that particular company. So it's amorphous powder form. Thank you very much.